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In the retinal degeneration model of light-treated BALB/cJ mice, treatment with indole-3-carbinol diminished INOS and NO· released by microglia, while concomitantly increasing the levels of anti-oxidants gene NQO1 and HMOX1

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Second, the same profile that makes it useful for skin, follicle, and wound tissue is the reason it has no plausible route to fat loss: energy-metabolism pathways are simply not where the signal lands