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This comprehensive GHK-Cu versus retinol comparison cuts through marketing claims to examine what human clinical trials actually demonstrate about collagen synthesis, fibroblast activation, cellular renewal pathways, anti-wrinkle efficacy, expression line smoothing, and skin barrier tolerance

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[DOI] [PubMed] [Google Scholar] 101.Macchi C., Giachi A., Fichtner I., Pedretti S., Sarzi-Puttini P., Mitro N., Corsini A., Ruscica M., Gualtierotti R