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For context only, the Phase 2 obesity trial published in the New England Journal of Medicine in 2023 studied once-weekly retatrutide at 1 mg, 4 mg, 8 mg, and 12 mg, with gradual escalation over the first weeks to improve tolerability

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[DOI] [PubMed] [Google Scholar] 83.Ilyas E.I., Nur B.M., Laksono S.P., Bahtiar A., Estuningtyas A., Vitasyana C., Kusmana D., Suyatna F.D., Tadjudin M.K., Freisleben H.J